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Cancer Research Center Hotline: Induction of Breast Cancer in Wild Type p53 Cells by BRCA1-IRIS Overexpression

Cells ability to evade cell death and to proliferate post geno-/cell-toxic stresses, likely leads to formation of cancer. Activation of p38MAPK and p53 following these stresses help protect cells against cancer development by initiating apoptosis. The duration of p38MAPK and p53 activation is regula...

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Détails bibliographiques
Auteur principal: ElShamy, Wael M
Format: Artigo
Langue:Inglês
Publié: University Clinical, Education & Research Associate (UCERA) 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118025/
https://ncbi.nlm.nih.gov/pubmed/20845286
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