Hepatitis B Virus genotypic differences map structurally close to NRTI resistance hot spots

Despite the availability of a Hepatitis B Virus (HBV) vaccine, there are approximately 350 million people that are chronically infected with this virus that can cause liver cirrhosis and hepatocellular carcinoma. Currently, most approved anti-HBV drugs are nucleoside RT inhibitors (NRTIs) that targe...

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Autors principals: Michailidis, Eleftherios, Singh, Kamlendra, Kirby, Karen A., Hachiya, Atsuko, Yoo, Wangdon, Hong, Sun Pyo, Kim, Soo-Ok, Folk, William R., Sarafianos, Stefan G.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325108/
https://ncbi.nlm.nih.gov/pubmed/22505793
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