Essential role for Stat5a/b in myeloproliferative neoplasms induced by BCR-ABL1 and JAK2(V617F) in mice

STAT5 proteins are constitutively activated in malignant cells from many patients with leukemia, including the myeloproliferative neoplasms (MPNs) chronic myeloid leukemia (CML) and polycythemia vera (PV), but whether STAT5 is essential for the pathogenesis of these diseases is not known. In the pre...

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Detalhes bibliográficos
Main Authors: Walz, Christoph, Ahmed, Wesam, Lazarides, Katherine, Betancur, Monica, Patel, Nihal, Hennighausen, Lothar, Zaleskas, Virginia M., Van Etten, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325042/
https://ncbi.nlm.nih.gov/pubmed/22234689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-397554
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