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Single Periocular Injection of Celecoxib-PLGA Microparticles Inhibits Diabetes-Induced Elevations in Retinal PGE(2), VEGF, and Vascular Leakage

PURPOSE: To determine whether celecoxib inhibits VEGF secretion from ARPE-19 cells and to investigate further the safety and effectiveness of periocular celecoxib-poly (lactide-co-glycolide; PLGA) microparticles in inhibiting elevations in retinal PGE(2), VEGF, and blood–tissue barrier leakage at th...

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Detalhes bibliográficos
Main Authors: Amrite, Aniruddha C., Ayalasomayajula, Surya P., Cheruvu, Narayan P. S., Kompella, Uday B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324981/
https://ncbi.nlm.nih.gov/pubmed/16505053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.05-0531
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