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Mitochondrial Acetylome Analysis in a Mouse Model of Alcohol-Induced Liver Injury Utilizing SIRT3 Knockout Mice

Mitochondrial protein hyperacetylation is a known consequence of sustained ethanol consumption and has been proposed to play a role in the pathogenesis of alcoholic liver disease (ALD). The mechanisms underlying this altered acetylome, however, remain unknown. The mitochondrial deacetylase sirtuin 3...

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Autors principals: Fritz, Kristofer S., Galligan, James J., Hirschey, Matthew D., Verdin, Eric, Petersen, Dennis R.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324946/
https://ncbi.nlm.nih.gov/pubmed/22309199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr2008384
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