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Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells
The anti-cancer effects of metformin, the most widely used drug for type 2 diabetes, alone or in combination with ionizing radiation were studied with MCF-7 human breast cancer cells and FSaII mouse fibrosarcoma cells. Clinically achievable concentrations of metformin caused significant clonogenic d...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3324825/ https://ncbi.nlm.nih.gov/pubmed/22500211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00362 |
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