The DNLZ/HEP zinc-binding subdomain is critical for regulation of the mitochondrial chaperone HSPA9

Human mitochondrial DNLZ/HEP regulates the catalytic activity and solubility of the mitochondrial hsp70 chaperone HSPA9. Here, we investigate the role that the DNLZ zinc-binding and C-terminal subdomains play in regulating HSPA9. We show that truncations lacking portions of the zinc-binding subdomai...

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Detalhes bibliográficos
Main Authors: Vu, Michael T, Zhai, Peng, Lee, Juhye, Guerra, Cecilia, Liu, Shirley, Gustin, Michael C, Silberg, Jonathan J
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324770/
https://ncbi.nlm.nih.gov/pubmed/22162012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2012
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