Ski Inhibits TGF-β/phospho-Smad3 Signaling and Accelerates Hypertrophic Differentiation in Chondrocytes

Since TGF-β/Smad signaling inhibits chondrocyte maturation, endogenous negative regulators of TGF-β signaling are likely also important regulators of the chondrocyte differentiation process. One such negative regulator, Ski, is an oncoprotein that is known to inhibit TGF-β/Smad3 signaling via its in...

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Main Authors: Kim, Kyung-Ok, Sampson, Erik R., Maynard, Robert D, O'Keefe, Regis J., Chen, Di, Drissi, Hicham, Rosier, Randy N., Hilton, Matthew J., Zuscik, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324639/
https://ncbi.nlm.nih.gov/pubmed/22461172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24089
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