Early induction of CCL7 downstream of TLR9 signaling promotes the development of robust immunity to cryptococcal infection

We investigated mechanisms by which TLR9 signaling promoted the development of the protective response to C. neoformans in mice with cryptococcal pneumonia. The afferent (week1) and efferent (week3) phase immune parameters were analyzed in the infected wild type (TLR9+/+) and TLR-deficient (TLR9-/-)...

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Autores principales: Qiu, Yafeng, Zeltzer, Stuart, Zhang, Yanmei, Wang, Fuyuan, Chen, Gwo-Hsiao, Dayrit, Jeremy, Murdock, Benjamin J., Bhan, Urvashi, Toews, Galen B., Osterholzer, John J., Standiford, Theodore J., Olszewski, Michal A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324623/
https://ncbi.nlm.nih.gov/pubmed/22422883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103053
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