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TGF-β-induced activation of mTOR complex 2 drives epithelial–mesenchymal transition and cell invasion
In cancer progression, carcinoma cells gain invasive behavior through a loss of epithelial characteristics and acquisition of mesenchymal properties, a process that can lead to epithelial–mesenchymal transition (EMT). TGF-β is a potent inducer of EMT, and increased TGF-β signaling in cancer cells is...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Company of Biologists
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3324583/ https://ncbi.nlm.nih.gov/pubmed/22399812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.095299 |
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