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PORCN Moonlights in a Wnt-Independent Pathway That Regulates Cancer Cell Proliferation
Porcupine (PORCN) is a membrane-bound O-acyl transferase that is required for the palmitoylation of Wnt proteins, and that is essential in diverse Wnt pathways for Wnt-Wntless (WLS) binding, Wnt secretion, and Wnt signaling activity. We tested if PORCN was required for the proliferation of transform...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3324524/ https://ncbi.nlm.nih.gov/pubmed/22509316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034532 |
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