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Computational image analysis of nuclear morphology associated with various nuclear-specific aging disorders

Computational image analysis is used in many areas of biological and medical research, but advanced techniques including machine learning remain underutilized. Here, we used automated segmentation and shape analyses, with pre-defined features and with computer generated components, to compare nuclei...

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Main Authors: Choi, Siwon, Wang, Wei, Ribeiro, Alexandrew J.S., Kalinowski, Agnieszka, Gregg, Siobhan Q., Opresko, Patricia L., Niedernhofer, Laura J., Rohde, Gustavo K., Dahl, Kris Noel
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2011
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324345/
https://ncbi.nlm.nih.gov/pubmed/22127259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.2.6.17798
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