Computational image analysis of nuclear morphology associated with various nuclear-specific aging disorders

Computational image analysis is used in many areas of biological and medical research, but advanced techniques including machine learning remain underutilized. Here, we used automated segmentation and shape analyses, with pre-defined features and with computer generated components, to compare nuclei...

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Bibliographic Details
Main Authors: Choi, Siwon, Wang, Wei, Ribeiro, Alexandrew J.S., Kalinowski, Agnieszka, Gregg, Siobhan Q., Opresko, Patricia L., Niedernhofer, Laura J., Rohde, Gustavo K., Dahl, Kris Noel
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2011
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324345/
https://ncbi.nlm.nih.gov/pubmed/22127259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.2.6.17798
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