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Copper Mediated Difluoromethylation of Aryl and Vinyl Iodides

Selectively fluorinated molecules are important as materials, pharmaceuticals, and agrochemicals, but their synthesis by simple, mild, laboratory methods is challenging. We report a straightforward method for the cross-coupling of a difluoromethyl group with readily available reagents to form difluo...

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Detalhes bibliográficos
Main Authors: Fier, Patrick S., Hartwig, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324264/
https://ncbi.nlm.nih.gov/pubmed/22397683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja301013h
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