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Changes in Regional Cerebral Blood Flow and Functional Connectivity in the Cholinergic Pathway Associated with Cognitive Performance in Subjects with Mild Alzheimer’s Disease after 12-week Donepezil Treatment

Acetylcholinesterase inhibitors (AChEIs), such as donepezil, have been shown to improve cognition in mild to moderate Alzheimer’s disease (AD) patients. In this paper, our goal is to determine the relationship between altered cerebral blood flow (CBF) and intrinsic functional network connectivity ch...

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Detalhes bibliográficos
Main Authors: Li, Wenjun, Antuono, Piero G., Xie, Chunming, Chen, Gang, Jones, Jennifer L., Ward, B. Douglas, Franczak, Malgorzata B., Goveas, Joseph S., Li, Shi-Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324180/
https://ncbi.nlm.nih.gov/pubmed/22245641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2011.12.077
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