Recovery of Hippocampal Network Connectivity Correlates with Cognitive Improvement in Mild Alzheimer's Disease Patients Treated with Donepezil Assessed by Resting-State fMRI

PURPOSE: To identify the neural correlates of cognitive improvement in mild AD subjects, following 12 weeks of donepezil treatment. MATERIALS AND METHODS: Resting-state functional connectivity MRI (R-fMRI) was used to measure the hippocampal functional connectivity (HFC) in 14 mild AD and 18 age-mat...

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Hlavní autoři: Goveas, Joseph S., Xie, Chunming, Ward, B. Douglas, Wu, Zhilin, Li, Wenjun, Franczak, Malgorzata, Jones, Jennifer L., Antuono, Piero G., Li, Shi-Jiang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177015/
https://ncbi.nlm.nih.gov/pubmed/21769962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmri.22662
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