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Structural basis for the enhanced stability of highly fluorinated proteins

Noncanonical amino acids have proved extremely useful for modifying the properties of proteins. Among them, extensively fluorinated (fluorous) amino acids seem particularly effective in increasing protein stability; however, in the absence of structural data, the basis of this stabilizing effect rem...

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Detalhes bibliográficos
Main Authors: Buer, Benjamin C., Meagher, Jennifer L., Stuckey, Jeanne A., Marsh, E. Neil G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324029/
https://ncbi.nlm.nih.gov/pubmed/22411812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120112109
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