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Structural basis for the enhanced stability of highly fluorinated proteins

Noncanonical amino acids have proved extremely useful for modifying the properties of proteins. Among them, extensively fluorinated (fluorous) amino acids seem particularly effective in increasing protein stability; however, in the absence of structural data, the basis of this stabilizing effect rem...

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Autors principals: Buer, Benjamin C., Meagher, Jennifer L., Stuckey, Jeanne A., Marsh, E. Neil G.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324029/
https://ncbi.nlm.nih.gov/pubmed/22411812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120112109
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