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Distribution of fixed beneficial mutations and the rate of adaptation in asexual populations

When large asexual populations adapt, competition between simultaneously segregating mutations slows the rate of adaptation and restricts the set of mutations that eventually fix. This phenomenon of interference arises from competition between mutations of different strengths as well as competition...

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Detalhes bibliográficos
Main Authors: Good, Benjamin H., Rouzine, Igor M., Balick, Daniel J., Hallatschek, Oskar, Desai, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323973/
https://ncbi.nlm.nih.gov/pubmed/22371564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119910109
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