Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells

The transcription factor Ebf1 is an important determinant of early B lymphopoiesis. To gain insight into the functions of Ebf1 at distinct stages of differentiation, we conditionally inactivated Ebf1. We found that Ebf1 is required for the proliferation, survival, and signaling of pro-B cells and pe...

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Autors principals: Györy, Ildiko, Boller, Sören, Nechanitzky, Robert, Mandel, Elizabeth, Pott, Sebastian, Liu, Edison, Grosschedl, Rudolf
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2012
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323878/
https://ncbi.nlm.nih.gov/pubmed/22431510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.187328.112
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