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Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells
The transcription factor Ebf1 is an important determinant of early B lymphopoiesis. To gain insight into the functions of Ebf1 at distinct stages of differentiation, we conditionally inactivated Ebf1. We found that Ebf1 is required for the proliferation, survival, and signaling of pro-B cells and pe...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323878/ https://ncbi.nlm.nih.gov/pubmed/22431510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.187328.112 |
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