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Hypoxic-Ischemic Injury in the Developing Brain: The Role of Reactive Oxygen Species Originating in Mitochondria

Mitochondrial dysfunction is the most fundamental mechanism of cell damage in cerebral hypoxia-ischemia and reperfusion. Mitochondrial respiratory chain (MRC) is increasingly recognized as a source for reactive oxygen species (ROS) in the postischemic tissue. Potentially, ROS originating in MRC can...

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Autori principali: Ten, Vadim S., Starkov, Anatoly
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323863/
https://ncbi.nlm.nih.gov/pubmed/22548167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/542976
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