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The selective inhibition of nuclear PKCζ restores the effectiveness of chemotherapeutic agents in chemoresistant cells

The atypical protein kinase C (PKC) isoform zeta (PKCζ) has been implicated in the intracellular transduction of mitogenic and apoptotic signals by acting on different signaling pathways. The key role of these processes in tumorigenesis suggests a possible involvement of PKCζ in this event. PKCζ is...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rimessi, Alessandro, Zecchini, Erika, Siviero, Roberta, Giorgi, Carlotta, Leo, Sara, Rizzuto, Rosario, Pinton, Paolo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323800/
https://ncbi.nlm.nih.gov/pubmed/22333579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.5.19520
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