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Ribonuclease A suggests how proteins self-chaperone against amyloid fiber formation

Genomic analyses have identified segments with high fiber-forming propensity in many proteins not known to form amyloid. Proteins are often protected from entering the amyloid state by molecular chaperones that permit them to fold in isolation from identical molecules; but, how do proteins self-chap...

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Detalhes bibliográficos
Main Authors: Teng, Poh K, Anderson, Natalie J, Goldschmidt, Lukasz, Sawaya, Michael R, Sambashivan, Shilpa, Eisenberg, David
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323778/
https://ncbi.nlm.nih.gov/pubmed/22095666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.754
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