Long-term effects of Alemtuzumab on regulatory and memory T cell subsets in kidney transplantation

BACKGROUND: Induction with lymphocyte-depleting antibodies is routinely employed to prevent rejection but often skews T cells towards memory. It is not fully understood which memory and regulatory T cell subsets are most affected and how they relate to clinical outcomes. METHODS: We analyzed T cells...

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Detalhes bibliográficos
Main Authors: Macedo, Camila, Walters, John T., Orkis, Elizabeth A., Isse, Kumiko, Elinoff, Beth D., Fedorek, Sheila P., McMichael, John M., Chalasani, Geetha, Randhawa, Parmjeet, Demetris, Anthony J., Zeevi, Adriana, Tan, Henkie, Shapiro, Ron, Landsittel, Doug, Lakkis, Fadi G., Metes, Diana
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323763/
https://ncbi.nlm.nih.gov/pubmed/22343334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e318247a717
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