T-bet(+)CD27(+)CD21(–) B cells poised for plasma cell differentiation during antibody-mediated rejection of kidney transplants

Alloimmune responses driven by donor-specific antibodies (DSAs) can lead to antibody-mediated rejection (ABMR) in organ transplantation. Yet, the cellular states underlying alloreactive B cell responses and the molecular components controlling them remain unclear. Using high-dimensional profiling of...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Louis, Kevin, Bailly, Elodie, Macedo, Camila, Lau, Louis, Ramaswami, Bala, Chang, Alexander, Chandran, Uma, Landsittel, Douglas, Gu, Xinyan, Chalasani, Geetha, Zeevi, Adriana, Randhawa, Parmjeet, Singh, Harinder, Lefaucheur, Carmen, Metes, Diana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262465/
https://ncbi.nlm.nih.gov/pubmed/34032636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.148881
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