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Bacterial persistence increases as environmental fitness decreases
Since persister cells cause chronic infections and since Escherichia coli toxin MqsR increases persisters, we used protein engineering to increase the toxicity of MqsR to gain insights into persister cell formation. Through two amino acid replacements that increased the stability of MqsR, toxicity a...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Publishing Ltd
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323757/ https://ncbi.nlm.nih.gov/pubmed/22221537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-7915.2011.00327.x |
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