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Bacterial persistence increases as environmental fitness decreases
Since persister cells cause chronic infections and since Escherichia coli toxin MqsR increases persisters, we used protein engineering to increase the toxicity of MqsR to gain insights into persister cell formation. Through two amino acid replacements that increased the stability of MqsR, toxicity a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323757/ https://ncbi.nlm.nih.gov/pubmed/22221537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-7915.2011.00327.x |
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