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Illegitimate V(D)J recombination involving non-antigen receptor loci in lymphoid malignancy

V(D)J recombination of antigen-receptor loci (IGH, IGK, IGL, TCRA, TCRB, TCRG, TCRD) is an essential mechanism that confers enormous diversity to the mammalian immune system. However, there are now at least six examples of intra-chromosomal interstitial deletions caused by aberrant V(D)J recombinati...

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Detalhes bibliográficos
Main Authors: Onozawa, Masahiro, Aplan, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323722/
https://ncbi.nlm.nih.gov/pubmed/22334400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.21942
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