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Illegitimate V(D)J recombination involving non-antigen receptor loci in lymphoid malignancy
V(D)J recombination of antigen-receptor loci (IGH, IGK, IGL, TCRA, TCRB, TCRG, TCRD) is an essential mechanism that confers enormous diversity to the mammalian immune system. However, there are now at least six examples of intra-chromosomal interstitial deletions caused by aberrant V(D)J recombinati...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323722/ https://ncbi.nlm.nih.gov/pubmed/22334400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.21942 |
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