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Disrupted GABA(A)R Trafficking and Synaptic Inhibition in a Mouse Model of Huntington’s Disease
Growing evidence suggests that Huntington’s disease (HD), a neurodegenerative movement disorder caused by the mutant huntingtin (htt) with an expanded polyglutamine (polyQ) repeat, is associated with the altered intracellular trafficking and synaptic function. GABA(A) receptors, the key determinant...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323696/ https://ncbi.nlm.nih.gov/pubmed/22402331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.02.015 |
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