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Disrupted GABA(A)R Trafficking and Synaptic Inhibition in a Mouse Model of Huntington’s Disease
Growing evidence suggests that Huntington’s disease (HD), a neurodegenerative movement disorder caused by the mutant huntingtin (htt) with an expanded polyglutamine (polyQ) repeat, is associated with the altered intracellular trafficking and synaptic function. GABA(A) receptors, the key determinant...
में बचाया:
| मुख्य लेखकों: | , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323696/ https://ncbi.nlm.nih.gov/pubmed/22402331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.02.015 |
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