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Polymeric Nanoparticles for Drug Delivery to the Central Nervous System

The central nervous system (CNS) poses a unique challenge for drug delivery. The blood-brain barrier significantly hinders the passage of systemically-delivered therapeutics and the brain extracellular matrix limits the distribution and longevity of locally-delivered agents. Polymeric nanoparticles...

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Autors principals: Patel, Toral, Zhou, Jiangbing, Piepmeier, Joseph M., Saltzman, W. Mark
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323692/
https://ncbi.nlm.nih.gov/pubmed/22210134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2011.12.006
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