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Optogenetic Mimicry of the Transient Activation of Dopamine Neurons by Natural Reward Is Sufficient for Operant Reinforcement

Activation of dopamine receptors in forebrain regions, for minutes or longer, is known to be sufficient for positive reinforcement of stimuli and actions. However, the firing rate of dopamine neurons is increased for only about 200 milliseconds following natural reward events that are better than ex...

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Detalhes bibliográficos
Main Authors: Kim, Kyung Man, Baratta, Michael V., Yang, Aimei, Lee, Doheon, Boyden, Edward S., Fiorillo, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323614/
https://ncbi.nlm.nih.gov/pubmed/22506004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033612
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