A Novel 3-Hydroxysteroid Dehydrogenase That Regulates Reproductive Development and Longevity

Endogenous small molecule metabolites that regulate animal longevity are emerging as a novel means to influence health and life span. In C. elegans, bile acid-like steroids called the dafachronic acids (DAs) regulate developmental timing and longevity through the conserved nuclear hormone receptor D...

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Main Authors: Wollam, Joshua, Magner, Daniel B., Magomedova, Lilia, Rass, Elisabeth, Shen, Yidong, Rottiers, Veerle, Habermann, Bianca, Cummins, Carolyn L., Antebi, Adam
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323522/
https://ncbi.nlm.nih.gov/pubmed/22505847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001305
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