In Vitro and In Vivo Efficacy of Ether Lipid Edelfosine against Leishmania spp. and SbV-Resistant Parasites

BACKGROUND: The leishmaniases are a complex of neglected tropical diseases caused by more than 20 Leishmania parasite species, for which available therapeutic arsenal is scarce and unsatisfactory. Pentavalent antimonials (SbV) are currently the first-line pharmacologic therapy for leishmaniasis worl...

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Autori principali: Varela-M, Rubén E., Villa-Pulgarin, Janny A., Yepes, Edward, Müller, Ingrid, Modolell, Manuel, Muñoz, Diana L., Robledo, Sara M., Muskus, Carlos E., López-Abán, Julio, Muro, Antonio, Vélez, Iván D., Mollinedo, Faustino
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323514/
https://ncbi.nlm.nih.gov/pubmed/22506086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001612
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