Dihydropteroate Synthase Gene Mutations in Pneumocystis and Sulfa Resistance

Pneumocystis pneumonia (PCP) remains a major cause of illness and death in HIV-infected persons. Sulfa drugs, trimethoprim-sulfamethoxazole (TMP-SMX) and dapsone are mainstays of PCP treatment and prophylaxis. While prophylaxis has reduced the incidence of PCP, its use has raised concerns about deve...

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Main Authors: Huang, Laurence, Crothers, Kristina, Atzori, Chiara, Benfield, Thomas, Miller, Robert, Rabodonirina, Meja, Helweg-Larsen, Jannik
Formato: Artigo
Idioma:Inglês
Publicado: Centers for Disease Control and Prevention 2004
Assuntos:
Perspective
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323267/
https://ncbi.nlm.nih.gov/pubmed/15504256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid1010.030994
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