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RWD domain: a recurring module in kinetochore architecture shown by a Ctf19–Mcm21 complex structure

The proteins Ctf19, Okp1, Mcm21 and Ame1 are the components of COMA, a subassembly of budding-yeast kinetochores. We have determined the crystal structure of a conserved COMA subcomplex—the Ctf19–Mcm21 heterodimer—from Kluyveromyces lactis. Both proteins contain ‘double-RWD' domains, which toge...

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Hlavní autoři: Schmitzberger, Florian, Harrison, Stephen C
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323139/
https://ncbi.nlm.nih.gov/pubmed/22322944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.1
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