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Nuclear IGF1R is a transcriptional co-activator of LEF1/TCF
Recent findings suggest that nuclear IGF1R binds to enhancer regions and functions as a transcriptional cofactor. However, the downstream transcriptional regulators of this pathway remain to be defined. Here, we show that nuclear IGF1R associates with the transcription factor LEF1 and increases prom...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323138/ https://ncbi.nlm.nih.gov/pubmed/22261717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.251 |
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