MicroRNA Profile of Circulating CD4-positive Regulatory T Cells in Human Adults and Impact of Differentially Expressed MicroRNAs on Expression of Two Genes Essential to Their Function

Regulatory T cells (Tregs) are characterized by a high expression of IL-2 receptor α chain (CD25) and of forkhead box P3 (FOXP3), the latter being essential for their development and function. Another major player in the regulatory function is the cytotoxic T-lymphocyte associated molecule-4 (CTLA-4...

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Detalles Bibliográficos
Autores principales: Fayyad-Kazan, Hussein, Rouas, Redouane, Fayyad-Kazan, Mohammad, Badran, Rabih, El Zein, Nabil, Lewalle, Philippe, Najar, Medhi, Hamade, Eva, Jebbawi, Fadi, Merimi, Makram, Romero, Pedro, Burny, Arsène, Badran, Bassam, Martiat, Philippe
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323050/
https://ncbi.nlm.nih.gov/pubmed/22294691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.337154
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