Identification and Structure Determination of Novel Anti-inflammatory Mediator Resolvin E3, 17,18-Dihydroxyeicosapentaenoic Acid

Bioactive mediators derived from omega-3 eicosapentaenoic acid (EPA) elicit potent anti-inflammatory actions. Here, we identified novel EPA metabolites, including 8,18-dihydroxyeicosapentaenoic acid (8,18-diHEPE), 11,18-diHEPE, 12,18-diHEPE, and 17,18-diHEPE from 18-HEPE. Unlike resolvins E1 and E2,...

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Bibliografiske detaljer
Main Authors: Isobe, Yosuke, Arita, Makoto, Matsueda, Shinnosuke, Iwamoto, Ryo, Fujihara, Takuji, Nakanishi, Hiroki, Taguchi, Ryo, Masuda, Koji, Sasaki, Kenji, Urabe, Daisuke, Inoue, Masayuki, Arai, Hiroyuki
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Lipids
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322993/
https://ncbi.nlm.nih.gov/pubmed/22275352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.340612
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