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STAT5 Protein Negatively Regulates T Follicular Helper (Tfh) Cell Generation and Function

Recent work has identified a new subset of CD4(+) T cells named as Tfh cells that are localized in germinal centers and critical in germinal center formation. Tfh cell differentiation is regulated by IL-6 and IL-21, possibly via STAT3 factor, and B cell lymphoma 6 (Bcl6) is specifically expressed in...

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Detalhes bibliográficos
Main Authors: Nurieva, Roza I., Podd, Andrew, Chen, Yuhong, Alekseev, Andrei M., Yu, Mei, Qi, Xiaopeng, Huang, Hua, Wen, Renren, Wang, Junmei, Li, Haiyan S., Watowich, Stephanie S., Qi, Hai, Dong, Chen, Wang, Demin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322890/
https://ncbi.nlm.nih.gov/pubmed/22318729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.324046
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