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Retinoic Acid Receptor α Mediates All-trans-retinoic Acid-induced Klf4 Gene Expression by Regulating Klf4 Promoter Activity in Vascular Smooth Muscle Cells
The transcription factor Krüppel-like factor 4 (KLF4) plays a critical role in vascular smooth muscle cell (VSMC) differentiation induced by all-trans-retinoic acid (ATRA). Although it has been demonstrated that ATRA stimulation augments both KLF4 protein and mRNA levels in VSMCs, the molecular mech...
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Prif Awduron: | , , , , |
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Fformat: | Artigo |
Iaith: | Inglês |
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American Society for Biochemistry and Molecular Biology
2012
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322846/ https://ncbi.nlm.nih.gov/pubmed/22337869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.321836 |
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