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Retinoic Acid Receptor α Mediates All-trans-retinoic Acid-induced Klf4 Gene Expression by Regulating Klf4 Promoter Activity in Vascular Smooth Muscle Cells

The transcription factor Krüppel-like factor 4 (KLF4) plays a critical role in vascular smooth muscle cell (VSMC) differentiation induced by all-trans-retinoic acid (ATRA). Although it has been demonstrated that ATRA stimulation augments both KLF4 protein and mRNA levels in VSMCs, the molecular mech...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shi, Jian-hong, Zheng, Bin, Chen, Si, Ma, Guo-yan, Wen, Jin-kun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322846/
https://ncbi.nlm.nih.gov/pubmed/22337869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.321836
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