Successful Prediction of Substrate-binding Pocket in SLC17 Transporter Sialin

Secondary active transporters from the SLC17 protein family are required for excitatory and purinergic synaptic transmission, sialic acid metabolism, and renal function, and several members are associated with inherited neurological or metabolic diseases. However, molecular tools to investigate thei...

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Bibliographic Details
Main Authors: Pietrancosta, Nicolas, Anne, Christine, Prescher, Horst, Ruivo, Raquel, Sagné, Corinne, Debacker, Cécile, Bertrand, Hugues-Olivier, Brossmer, Reinhard, Acher, Francine, Gasnier, Bruno
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Membrane Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322832/
https://ncbi.nlm.nih.gov/pubmed/22334707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.313056
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