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Peptide Nucleic Acids as Tools for Single-Molecule Sequence Detection and Manipulation
The ability to strongly and sequence-specifically attach modifications such as fluorophores and haptens to individual double-stranded (ds) DNA molecules is critical to a variety of single-molecule experiments. We propose using modified peptide nucleic acids (PNAs) for this purpose and implement them...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322611/ https://ncbi.nlm.nih.gov/pubmed/20923183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl102986v |
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