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Peptide Nucleic Acids as Tools for Single-Molecule Sequence Detection and Manipulation

The ability to strongly and sequence-specifically attach modifications such as fluorophores and haptens to individual double-stranded (ds) DNA molecules is critical to a variety of single-molecule experiments. We propose using modified peptide nucleic acids (PNAs) for this purpose and implement them...

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Bibliografiske detaljer
Main Authors: Zohar, Hagar, Hetherington, Craig L., Bustamante, Carlos J., Muller, Susan J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322611/
https://ncbi.nlm.nih.gov/pubmed/20923183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl102986v
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