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The role of lamin A in cytoskeleton organization in colorectal cancer cells: A proteomic investigation

Upregulated expression of lamin A has been implicated in increased cell invasiveness and mortality in colorectal cancer. Here we use quantitative proteomics to investigate lamin A regulated changes in the cytoskeleton that might underpin increased cell motility. Using siRNA knockdown of lamin A in a...

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Main Authors: Foster, Clare R, Robson, Joanne L, Simon, William J, Twigg, Jeremy, Cruikshank, Derek, Wilson, Robert G, Hutchison, Christopher J
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322584/
https://ncbi.nlm.nih.gov/pubmed/21983087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.2.5.17775
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