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Human iPS-derived retinal pigment epithelium (RPE) cells exhibit ion transport, membrane potential, polarized VEGF secretion and gene expression pattern similar to native RPE

Aged-related macular degeneration (AMD) is one of the major causes of blindness in aging population and progresses with death of retinal pigment epithelium (RPE) and photoreceptor degeneration inducing impairment of central vision. Discovery of human induced pluripotent stem (hiPS) cells has opened...

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Detalhes bibliográficos
Main Authors: Kokkinaki, Maria, Sahibzada, Niaz, Golestaneh, Nady
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322554/
https://ncbi.nlm.nih.gov/pubmed/21480547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.635
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