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Human iPS-derived retinal pigment epithelium (RPE) cells exhibit ion transport, membrane potential, polarized VEGF secretion and gene expression pattern similar to native RPE

Aged-related macular degeneration (AMD) is one of the major causes of blindness in aging population and progresses with death of retinal pigment epithelium (RPE) and photoreceptor degeneration inducing impairment of central vision. Discovery of human induced pluripotent stem (hiPS) cells has opened...

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Autors principals: Kokkinaki, Maria, Sahibzada, Niaz, Golestaneh, Nady
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322554/
https://ncbi.nlm.nih.gov/pubmed/21480547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.635
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