An HIV-1 clade A/E DNA prime, recombinant fowlpox virus boost vaccine is safe, but non-immunogenic in a randomized phase 1/11a trial in Thai volunteers at low risk of HIV infection

BACKGROUND: Previously demonstrated safe and highly immunogenic in non-human primates, this study assessed DNA (pHIS-HIV-AE) prime, recombinant fowlpox (rFPV-HIV-AE) boost vaccines in humans. RESULTS: Eight participants (6 active vaccine, 2 placebo) received all vaccinations; local and systemic reac...

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Detalhes bibliográficos
Main Authors: Hemachandra, Atchriya, Puls, Rebekah L, Sirivichayakul, Sunee, Kerr, Stephen, Thantiworasit, Pattarawat, Ubolyam, Sasiwimol, Cooper, David A, Emery, Sean, Phanuphak, Praphan, Kelleher, Anthony, Ruxrungtham, Kiat
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322532/
https://ncbi.nlm.nih.gov/pubmed/20864808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.6.10.12635
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