A Novel Immunodominant CD8+ T Cell Response Restricted by a Common HLA-C Allele Targets a Conserved Region of Gag HIV-1 Clade CRF01_AE Infected Thais

BACKGROUND: CD8+ T cell responses play an important role in the control of HIV-1. The extensive sequence diversity of HIV-1 represents a critical hurdle to developing an effective HIV-1 vaccine, and it is likely that regional-specific vaccine strains will be required to overcome the diversity of the...

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Main Authors: Buranapraditkun, Supranee, Hempel, Ursula, Pitakpolrat, Patrawadee, Allgaier, Rachel L., Thantivorasit, Pattarawat, Lorenzen, Sven-Iver, Sirivichayakul, Sunee, Hildebrand, William H., Altfeld, Marcus, Brander, Christian, Walker, Bruce D., Phanuphak, Praphan, Hansasuta, Pokrath, Rowland-Jones, Sarah L., Allen, Todd M., Ruxrungtham, Kiat
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161737/
https://ncbi.nlm.nih.gov/pubmed/21887282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023603
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