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Interplay of bromodomain and histone acetylation in the regulation of p300-dependent genes

The bromodomain is an evolutionarily conserved motif found in many transcriptional activators including p300 which contains an intrinsic histone acetyltransferase activity and is a general coactivator for many transcription factors. One mode of bromodomain action is to serve as a binding module to r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Jihong, Ghazawi, Feras M, Li, Qiao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322497/
https://ncbi.nlm.nih.gov/pubmed/20505343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.5.6.12224
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